Managing Dyslipidemia

Managing Dyslipidemia


Secondary causes contribute to many cases of dyslipidemia in adults. The most common include:

A sedentary lifestyle with excessive dietary intake of saturated fat, cholesterol, and trans fats.

Diabetes mellitus

Alcohol overuse

Chronic kidney disease


Primary biliary cirrhosis and other cholestatic liver diseases

Drugs, such as thiazides, β-blockers, retinoids, highly active antiretroviral agents etc

Patients with type 2 diabetes are especially at risk. The combination may be a consequence of obesity, poor control of diabetes, or both, which may increase circulating free fatty acids (FFAs), leading to increased hepatic very-low-density lipoprotein (VLDL) production.


Lose weight – Usually, the best treatment for people is to lose weight if they are overweight, stop smoking if they smoke, decrease the total amount of saturated fat and cholesterol in their diet, increase physical activity, and then, if necessary, take a lipid-lowering drug.
Exercise – Regular physical activity can help lower triglyceride levels and increase the HDL cholesterol level. An example is walking briskly for at least 30 minutes 5 times a week.
Decrease saturated fats in the diet – The goal of dietary therapy is to reduce elevated total cholesterol and LDL cholesterol levels to the target values while maintaining a nutritious diet.
Lipid-lowering drugs – Treatment with lipid-lowering drugs depends not only on the lipid levels but also on whether coronary artery disease, diabetes, or other major risk factors for coronary artery disease are present.

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